2-Amino-5-chlorobenzophenone

Gusaba
Metabolite ya Diazepam;byari bifite intege nke cyane anticonvulsant.

Abahuza imiti.Gukora ibiyobyabwenge nka Librium na Valium.
Ingaruka ku bidukikije
Kubangamira gato amazi, ntukemere ko amazi menshi cyangwa menshi ahura n’amazi yo mu butaka, inzira y’amazi cyangwa imiyoboro y’imyanda, kandi ntusohore ibikoresho mu bidukikije utabiherewe uburenganzira na leta.

Ibyiza no Guhagarara
Ihindagurika ku bushyuhe bw’ibidukikije n’umuvuduko, irinde guhura na oxyde

Uburyo bwo kubika
Komeza ibintu bifunze neza kandi ubike ahantu hakonje, humye mubintu byuzuye.

Uburyo bwa Synthesis
(1) Byakozwe nigisubizo cya p-chloroaniline hamwe na chloride ya benzoyl.Ongeramo p-chlorobenzene mumasafuriya yerekana ibirahuri kuri 70 ° C cyangwa munsi yayo, shyiramo chloride ya anhydrous zinc, ongeramo benzoyl chloride itonyanga hamwe, hanyuma uzamure ubushyuhe, ufate kuri 195-205 ° C kuri 2h, oza inshuro eshanu hamwe amazi ashyushye kuri 90-95 ° C (urwego rwamazi nigisubizo cyo gukaraba bigarura aside benzoic na chloride ya zinc) kuri 100 ° C, ongeramo aside sulfurike gahoro gahoro, ufate kuri 142 ° C kuri 40min.Ibikomeye bigwa mumazi.Mugukangura, pH ihindurwa na alkali yamazi kugirango itarenza 1 hanyuma uyungurure kuri 20-25 ° C.Akayunguruzo kagaruwe nka p-chloroaniline.Agatsima kayunguruzo kavanze kandi gahagarikwa mumazi, kutabogama kuri pH = 6, kuyungurura byumye, gukaraba n'amazi kugirango bitagira aho bibogamiye kandi byumye kugirango ubone ibicuruzwa bitavanze.Noneho shyiramo inshuro 6-7 Ethanol, 6% ikora karubone ikora, kugaruka kuri 30min, kuyungurura no korohereza, byumye kugirango ubone ibicuruzwa byiza.(2) p-Nitrochlorobenzene na cyanobenzyl impeta ihuza kugirango ubone isoxazole, hanyuma fungura impeta, kugabanuka kugirango ubone.