Doxifluridine

Gusaba
1. Nka prodrug ya 5-Flurouridine.Fluorine pyrimidine nucleoside hamwe nibikorwa bya cytostatike.Ivuriro rikoreshwa muri kanseri yo mu gifu, kanseri yibara, kanseri y'ibere, igipimo cyo kwandura gishobora kugera kuri 30%
2. Nkumuhuza wimiti igabanya ubukana bwa Fluorouracil

Intangiriro yo gukoresha
1. Imiti igabanya ubukana bwa Fluorouracil ibanziriza fluorouracil.Enzyme thymidine phosphorylase, igaragara mu ngingo zifata ibibyimba, ikora kuri yo kugirango ihindure fluorouracil mu kibyimba, bityo igire ingaruka zo kurwanya ikibyimba.Ifite umwihariko wo kurwanya ibibyimba n'uburozi buke.Ikoreshwa mubuvuzi muri kanseri yo mu gifu, kanseri yibara na kanseri y'ibere, hamwe no kwandura kugera kuri 30% cyangwa irenga.
2. Hagati ya farumasi.
3. Numuti urwanya antitumour, imiti ibanziriza fluorouracil (5-FU), ihindurwamo fluorouracil yubusa nigikorwa cya pyrimidine nucleoside phosphorylase mumyanya yibibyimba, bityo bikabuza biosynthesis ya ADN na RNA mungirangingo yibibyimba kandi ikerekana ingaruka za antitumour.Kubera ko ibikorwa byiyi misemburo biri hejuru mubice byibyimba kuruta mubice bisanzwe, guhindura 5-FU muri 5-FU mubice byibyimba byihuse kandi bitoranya kubyimba.Ikoreshwa mukuvura kanseri yamabere, igifu na rectal kandi ifite uburozi buke.