Orlistat

Gusaba
Guhuza indyo yuzuye ya calorie ikwiranye no kuvura igihe kirekire kubantu bafite umubyibuho ukabije kandi ufite ibiro byinshi, harimo nabafite ibibazo by’umubyibuho ukabije.Ifite ingaruka zo kugenzura ibiro birebire (kugabanya ibiro, kubungabunga ibiro no kwirinda kugaruka).Gufata ibiyobyabwenge birashobora kugabanya umuvuduko w’impanuka ziterwa n’umubyibuho ukabije n’izindi ndwara ziterwa n'umubyibuho ukabije, harimo hypercholesterolemia na diyabete yo mu bwoko bwa 2.

Orlistat numukozi utari CNS ukora ibikorwa byo kuvura umubyibuho ukabije.Ikora gusa mu nzira ya gastrointestinal, irinda hydrolysis ya triacylglycerol muri aside irike yubusa na monoacylglyceride ibuza lipase mu nzira ya gastrointestinal, kugabanya kwinjiza amavuta yimirire (triacylglycerol) na mucosa yo munda, no guteza imbere kurandura amavuta mumubiri. .Lipase ni enzyme ikenewe mu kubora ibinure mu nzira ya gastrointestinal.Iki gicuruzwa gishobora guhuza ibisigisigi bya serine ya lipase gastric na pancreatic lipase kugirango idakora lipase, kugirango idashobora kubora ibinure mubiribwa muri acide yubusa kandi bikabuza gukoresha no kwinjiza amavuta.
Icyitonderwa: 1. Abarwayi bafite umubyibuho ukabije barwaye diyabete yo mu bwoko bwa 2 batakaza ibiro nyuma yo kuvurwa niki gicuruzwa, akenshi bikajyana no kurwanya indwara ya glycemic, kandi bakeneye guhindura imiti ya hypoglycemic kugirango birinde hypoglycemia.
2. Abagore batwite n'abonsa, abana bari munsi yimyaka 18 ningimbi ntibigeze biga kubwumutekano no gukora neza, ntibakoreshe.