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Ibicuruzwa

Thymidine

Ibisobanuro bigufi:

Amakuru rusange
Izina ryibicuruzwa : Thymidine
URUBANZA No.:50-89-5
EINECS yinjira nimero : 200-070-4
Imiterere :
Inzira ya molekulari : C10H14N2O5
Uburemere bwa molekuline : 242.23


Ibicuruzwa birambuye

Ibicuruzwa

Imiterere

3

Umubiri
Kugaragara Pow Ifu yera ya Crystalline
Ibara : cyera Kuri hafi Yera
Ubucucike : 1.3129 (Ikigereranyo gikabije)
Gushonga : 186-188 ° c (lit.)
Ingingo yo guteka : 385.05 ° c (Ikigereranyo gikabije)
Kugabanuka : 33 ° (c = 1, 1mol / l Naoh)
Guhinduranya byihariye : 18.6 º (c = 3, H2o)
Imiterere yo kubika : 2-8 ° c
Ikintu cya Acide (pka) : pk1: 9.79; pk2: 12.85 (25 ° c)
Kuzunguruka : α] 20 / d + 19 ± 1 °, C = 1% Muri H2o
Gukemura mumazi : gushonga
Igihagararo : gihamye.Ntibishobora Kubangikanya na Oxidizing ikomeye

Amakuru yumutekano
Icyiciro cya Hazard : Ntabwo ari ibintu biteje akaga
Ibicuruzwa biteje akaga bitwara no :
Icyiciro cyo gupakira :

Gusaba
1.Yakoreshejwe nka farumasi hagati yo guhuza imiti igabanya ubukana bwa virusi itera sida.
2.Nkuko hagati ya Zivdodine

Gukoresha :
Thymidine ni deoxyribonucleoside irimo base ya thymine.Thymidine ni nucleoside ikorwa muguhuza thymidine na D-ribose binyuze muri bond-glycosidic.Thymidine ikoreshwa mugutegura imiti igabanya ubukana bwa SIDA (urugero: zidofuridine, stavudine) no muguhuza imiti igabanya ubukana.Irashobora kandi gukoreshwa nka farumasi hagati kandi ikoherezwa hanze.
Bioactivite :
Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThChemicalbookyd, NSC21548) ni nucleoside ya pyrimidine igizwe na thymine, umusingi wa pyrimidine ufatanije nisukari deoxyribose.Nkibigize ADN, thymine nucleoside ihuza na adenine muri ADN kabiri helix.


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