Acide Folike

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Acide Folike ni vitamine ikabura amazi hamwe na molekuline ya C19H19N7O6, yitwa rero kuko iba myinshi mumababi yicyatsi, izwi kandi nka acide pteroylglutamic.Ibaho muburyo butandukanye muri kamere kandi ibice byababyeyi ni ihuriro ryibice 3: pteridine, p-aminobenzoic aside na aside glutamic.
Acide Folike irimo grutamyl imwe cyangwa nyinshi, kandi muburyo busanzwe bwa aside folike ni aside polyglutamic.Ubwoko bwibinyabuzima bwa aside folike ni tetrahydrofolate.Acide Folike ni kristaline yumuhondo kandi igashonga gato mumazi, ariko umunyu wa sodiumi ushonga cyane mumazi.Ntishobora gukemuka muri Ethanol.Isenyuka byoroshye mubisubizo bya acide kandi nayo ntigihinduka ubushyuhe, itakara byoroshye mubushyuhe bwicyumba, kandi irashobora kwangirika cyane kumurika.
Acide Folike yinjira mu mubiri haba mu buryo bworoshye kandi bworoshye no gukwirakwizwa, cyane cyane mu gice cyo hejuru cy'amara mato.Igipimo cyo kwinjiza aside folike yagabanutse ni kinini, glutamyl ninshi igabanya umuvuduko wo kwinjiza, kandi iyinjizwa ryoroherezwa na glucose na vitamine C. Nyuma yo kwinjizwa, aside folike ibikwa mu rukuta rw amara, umwijima, igufwa ry amagufwa nizindi ngingo, kandi igabanutse kuri physiologique ikora tetrahydrofolate (THFA cyangwa FH4) na enzyme NADPH, igira uruhare muguhuza purine na pyrimidine.Acide Folike rero igira uruhare runini muguhindura poroteyine no kugabana ingirabuzimafatizo no gukura, kandi bigatera ishingwa ry'uturemangingo dusanzwe dutukura.Kubura aside folike birashobora gutuma igabanuka ry'umusemburo wa hemoglobine mu ngirangingo z'amaraso atukura no kugabanuka kw'imikurire ya selile, bikaviramo kubura amaraso ya megaloblastique.