Vuba aha, abashakashatsi bo muri kaminuza ya leta ya Jeworujiya na kaminuza ya Tufts basanze aside folike ishobora gutera ikwirakwizwa ry’ingirabuzimafatizo binyuze mu muco wa vitro ndetse na sisitemu y’icyitegererezo cy’inyamaswa, bidashingiye ku ruhare rwayo nka vitamine, kandi ubushakashatsi bujyanye na bwo bwatangajwe mu kinyamakuru mpuzamahanga Akagari ko Gutezimbere.
Acide Folike, yaba vitamine B yiyongera cyangwa aside folike isanzwe ikomoka ku biryo, irakenewe mu mikorere isanzwe ya selile zose z'umubiri kandi ni ingenzi mu gukumira inenge ziterambere zikivuka.Muri iyo ngingo, abashakashatsi babanje kubona ko ingirabuzimafatizo zikuze zishobora kugenzurwa n’ikintu gikomoka hanze y’umubiri w’inyamaswa, ni ukuvuga aside folike ikomoka kuri bagiteri, nka moderi ya nematode nka Caenorhabditis elegans.
Umushakashatsi Edward Kipreos yavuze ko ubushakashatsi bwacu bwerekana ko ingirangingo ngengabuzima ziri muri elegans caenorhabditis zishobora kugabanywa no gukurura folate ituruka ku mirire ya bagiteri;aside folike ni vitamine B ikenewe, ariko abashakashatsi basanze ubushobozi bwa aside folike idasanzwe yo gukangura ingirabuzimafatizo idashobora guterwa n'uruhare rwayo nka vitamine B, ishobora kwerekana ko aside folike igira uruhare rutaziguye nka molekile yerekana.
Ubusanzwe aside folike ibaho ikunda kuza muburyo bwinshi bwa chimique, nka aside folike mu biryo cyangwa uburyo bwa metabolique ikora bwa aside folike mu mubiri wumuntu, kandi aside folike nayo igaragara muburyo bukomeye bwogukora mubiribwa bikomejwe hamwe na vitamine.Acide Folique yavumbuwe mu 1945, kuva umunsi yavumbuwe, abashakashatsi benshi barayize cyane, none ubu hari impapuro zirenga 50.000 zubushakashatsi bujyanye na aside folike, ariko ubu bushakashatsi burihariye, kuko ubushakashatsi bugaragaza uruhare rushya ya aside folike, kuruta uruhare rwa aside folike yagaragaye mubushakashatsi bwabanje.
Acide Folique kuri ubu yongewe ku binyampeke muri Amerika no mu bindi bihugu, kandi kongera aside folike birashobora gufasha cyane kugabanya ivuka ry’abana bafite ubumuga bwo mu mikurire y’imitsi, ariko uruhare rwa aside folike yo kudashingira kuri vitamine irashobora kumufasha gutanga inzira ya kabiri igana umubiri w'umuntu.Muri iyo ngingo, abashakashatsi basanze reseptor idasanzwe ya folate yitwa FOLR-1 ikenewe kugira ngo imikurire y’ingirabuzimafatizo y’imyororokere mu mubiri wa Caenorhabditis elegans.
Muri icyo gihe kandi, abashakashatsi barebeye hamwe kandi uburyo bwa reseptor ya FOLR-1 itera ibibyimba bya mikorobe muri elegans ya caenorhabditis, ishobora kuba imeze nk'iyakirwa na aside folike itera kanseri idasanzwe mu binyabuzima by'abantu;byumvikane ko ibyakirwa bishobora kuba bidakenewe mu gutwara aside folike mu ngirabuzimafatizo kugira ngo ikoreshe vitamine, ariko irashobora gutera amacakubiri.Hanyuma, abashakashatsi bavuga ko ubushakashatsi bushobora no kuduha igikoresho gishya cyo gufasha kwiga ibinyabuzima nyamukuru byerekana imiterere.
Igihe cyo kohereza: Werurwe-30-2022