Indole-3-methanol

Ibisobanuro bigufi:

Indole-3-methanol nigiterwa gishya cya kabiri metabolite ikorerwa mu mboga zibisi, zishobora kuvanwa mu mboga zikomeye (nka broccoli, radis na kawuseri).Indole-3-karbinol ni ikibyimba cya chemopreventive.Indole-3-karbinol irashobora kubuza kubaho no gukura kw'ibibyimba bitandukanye.Indole-3-methanol yakoreshejwe mugukingira aside poly lactique co glycolic aside (PLGA) kugirango yige ingaruka zayo kuri anticancer kumabere adenocarcinoma epithelial selile (MCF7), colon adenocarcinoma epithelial selile (Caco2) na kanseri ya prostate epithelial selile (PC3) muri vitro.Ikoreshwa kandi nka inducer ya cytochrome P4501A (CYP1A).

Ohereza imeri kuri twe

Ibicuruzwa birambuye

Ibicuruzwa

Ibisobanuro

Indole-3-methanol (I3C) ikora reseptor ya hydrocarubone ya hydrocarubone (AHR) kandi itera G1 ingirabuzimafatizo hamwe na apoptose.Kubwibyo, ni anticancer agent.Byongeye kandi, itera metabolism ya estradiol itera enzyme ya cytochrome P450.Kubwibyo, I3C ifatwa nkumuti mwiza wa chimiotherapie wubwoko butandukanye bwa kanseri, harimo kanseri yamabere, kanseri ya prostate, kanseri yumura na leukemia.Indole-3-methanol irashobora gusa gutera apoptose yingirangingo za kanseri, ikaba ifite umutekano kandi idafite cytotoxic kuri selile idafite ibibyimba.Kubera imikorere yayo myiza, idafite uburozi na kamere irwanya ibibyimba, indole-3-methanol irashobora gukoreshwa nkumwe mubakandida ba kanseri yo kwirinda no kuvura imiti.

Amakuru y'ibicuruzwa

Cas No ： 700-06-1

Isuku ： ≥98%

Inzira ： C9H9NO

Amata Wt.： 147.17

Izina ryimiti ： INDOLE-3-CARBINOL

Synonym: Indole-3-karbinol, 99.5%; Indole-3-karbinol98%;(1H-Indol-3-yl) -methano;Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL; INDOLE-3-CARBINOL: 3-INDOLEMETHANOL; INDOLE-3-CARBINOL (RG); 3-HYDROXYMETHYLINDOLE (INDOLE-3-CARBINOL)

Ingingo yo gushonga ： 96-99 ° C.

Ingingo yo guteka ： 267.28 ° C.

Kugaragara ： Hanze-yera kugeza umuhondo-orange ifu ya kristaline cyangwa flake